Interactions of cardiolipin and lyso-cardiolipins with cytochrome c and tBid: conflict or assistance in apoptosis
نویسندگان
چکیده
منابع مشابه
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Conformational properties of cardiolipin-bound cytochrome c.
Interactions of cytochrome c (cyt c) with cardiolipin (CL) are important for both electron transfer and apoptotic functions of this protein. A sluggish peroxidase in its native state, when bound to CL, cyt c catalyzes CL peroxidation, which contributes to the protein apoptotic release. The heterogeneous CL-bound cyt c ensemble is difficult to characterize with traditional structural methods and...
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2006
ISSN: 1350-9047,1476-5403
DOI: 10.1038/sj.cdd.4402068